Somalian, Hyderabadi trying to sneak into Nepal questioned for Hyderabad blasts

MOTIHARI (BIHAR): A Somalian and a Hyderabad youth arrested here while trying to sneak into Nepal were questioned on Sunday by security forces and central agencies, even as a senior district police officer said no link of the duo with the twin blasts in Hyderabad has come to light so far.

30-year-old Somalian national Abdullah Umran Makran and his associate Mohammad Adam of Hyderabad were nabbed by immigration officials with the help of Bihar Police in Haraiya village on Saturday while trying to sneak into Nepal without valid documents. They have been remanded in judicial custody on Sunday.

Preliminary information said that the two had landed in Raxual by train from New Delhi on Saturday after travelling from Hyderabad to the national capital.

An FIR has been lodged under Foreigners Act with the Raxual police station against the two on the statement of immigration officials, superintendent of police Ganesh Kumar told PTI.

The Somalian and the Hyderabad youth were produced in the court of sub-divisional judicial magistrate (SDJM), Raxual, Mahesh Prasad who sent them to judicial custody for a fortnight.

A laptop, a mobile, a camera and driving licence made in Hyderabad have been seized from the two, the sources said adding there was a photograph of Secunderabad Railway station in the camera.

Central intelligence agencies and Military Intelligence officials along with the state police have questioned the two, police sources said.

SP Ganesh Kumar said during questioning no link with the blasts has come to light.

"It has come to light that the Somalian had an affair with a Hyderabad girl," he said.

Kumar said the Somalian and his associate staying in Kathmandu had recently illegally entered into East Champaran district in a bid to collect papers for passport preparation and were returning to Nepal the same way.

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FDA approves new targeted breast cancer drug


WASHINGTON (AP) — The Food and Drug Administration has approved a first-of-a-kind breast cancer medication that targets tumor cells while sparing healthy ones.


The drug Kadcyla from Roche combines the established drug Herceptin with a powerful chemotherapy drug and a third chemical linking the medicines together. The chemical keeps the cocktail intact until it binds to a cancer cell, delivering a potent dose of anti-tumor poison.


Cancer researchers say the drug is an important step forward because it delivers more medication while reducing the unpleasant side effects of chemotherapy.


"This antibody goes seeking out the tumor cells, gets internalized and then explodes them from within. So it's very kind and gentle on the patients — there's no hair loss, no nausea, no vomiting," said Dr. Melody Cobleigh of Rush University Medical Center. "It's a revolutionary way of treating cancer."


Cobleigh helped conduct the key studies of the drug at the Chicago facility.


The FDA approved the new treatment for about 20 percent of breast cancer patients with a form of the disease that is typically more aggressive and less responsive to hormone therapy. These patients have tumors that overproduce a protein known as HER-2. Breast cancer is the second most deadly form of cancer in U.S. women, and is expected to kill more than 39,000 Americans this year, according to the National Cancer Institute.


The approval will help Roche's Genentech unit build on the blockbuster success of Herceptin, which has long dominated the breast cancer marketplace. The drug had sales of roughly $6 billion last year.


Genentech said Friday that Kadcyla will cost $9,800 per month, compared to $4,500 per month for regular Herceptin. The company estimates a full course of Kadcyla, about nine months of medicine, will cost $94,000.


FDA scientists said they approved the drug based on company studies showing Kadcyla delayed the progression of breast cancer by several months. Researchers reported last year that patients treated with the drug lived 9.6 months before death or the spread of their disease, compared with a little more than six months for patients treated with two other standard drugs, Tykerb and Xeloda.


Overall, patients taking Kadcyla lived about 2.6 years, compared with 2 years for patients taking the other drugs.


FDA specifically approved the drug for patients with advanced breast cancer who have already been treated with Herceptin and taxane, a widely used chemotherapy drug. Doctors are not required to follow FDA prescribing guidelines, and cancer researchers say the drug could have great potential in patients with earlier forms of breast cancer


Kadcyla will carry a boxed warning, the most severe type, alerting doctors and patients that the drug can cause liver toxicity, heart problems and potentially death. The drug can also cause severe birth defects and should not be used by pregnant women.


Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.-based ImmunoGen. The company developed the chemical that keeps the drug cocktail together and is scheduled to receive a $10.5 million payment from Genentech on the FDA decision. The company will also receive additional royalties on the drug's sales.


Shares of ImmunoGen Inc. rose 2 cents to $14.32 in afternoon trading. The stock has ttraded in a 52-wek range of $10.85 to $18.10.


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6 Leaking Tanks Are Wash. Nuke Site's Latest Woe











Federal and state officials say six underground tanks holding a brew of radioactive and toxic waste are leaking at the country's most contaminated nuclear site in south-central Washington, raising concerns about delays for emptying the aging tanks.



The leaking materials at Hanford Nuclear Reservation pose no immediate risk to public safety or the environment because it would take perhaps years for the chemicals to reach groundwater, Washington Gov. Jay Inslee said Friday.



But the news has renewed discussion over delays for emptying the tanks, which were installed decades ago and are long past their intended 20-year life span.



"None of these tanks would be acceptable for use today. They are all beyond their design life. None of them should be in service," said Tom Carpenter of Hanford Challenge, a Hanford watchdog group. "And yet, they're holding two-thirds of the nation's high-level nuclear waste."



Just last week, state officials announced that one of Hanford's 177 tanks was leaking 150 to 300 gallons a year, posing a risk to groundwater and rivers. So far, nearby monitoring wells haven't detected higher radioactivity levels.



Inslee then traveled to Washington, D.C., to discuss the problem with federal officials, learning in meetings Friday that six tanks are leaking.






AP Photo/Shannon Dininny, File








The declining waste levels in the six tanks were missed because only a narrow band of measurements was evaluated, rather than a wider band that would have shown the levels changing over time, Inslee said.



"It's like if you're trying to determine if climate change is happening, only looking at the data for today," he said. "Perhaps human error, the protocol did not call for it. But that's not the most important thing at the moment. The important thing now is to find and address the leakers."



Department of Energy spokeswoman Lindsey Geisler said there was no immediate health risk and that federal officials would work with Washington state to address the matter.



Regardless, Sen. Ron Wyden, the new chairman of the Senate Energy and Natural Resources Committee, will ask the Government Accountability Office to investigate Hanford's tank monitoring and maintenance program, said his spokesman, Tom Towslee.



The federal government built the Hanford facility at the height of World War II as part of the Manhattan Project to build the atomic bomb. The remote site produced plutonium for the bomb dropped on Nagasaki, Japan, and continued supporting the nation's nuclear weapons arsenal for years.



Today, it is the most contaminated nuclear site in the country, still surrounded by sagebrush but with Washington's Tri-Cities of Richland, Kennewick and Pasco several miles downriver.



Several years ago, workers at Hanford completed two of three projects deemed urgent risks to the public and the environment, removing all weapons-grade plutonium from the site and emptying leaky pools that held spent nuclear fuel just 400 yards from the river.



But successes at the site often are overshadowed by delays, budget overruns and technological challenges. Nowhere have those challenges been more apparent than in Hanford's central plateau, home to the site's third most urgent project: emptying the tanks.



Hanford's tanks hold some 53 million gallons of highly radioactive waste — enough to fill dozens of Olympic-size swimming pools — and many of those tanks are known to have leaked in the past. An estimated 1 million gallons of radioactive liquid has already leaked there.





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Football: Singapore's Adam Swandi secures 2-year contract with FC Metz






SINGAPORE: Sixteen-year-old Adam Swandi has secured a two-year deal with French Football Club FC Metz.

He was the Most Valuable Player of the Singapore National Football Academy Under-16 team at the Lion City Cup tournament last June.

Adam Swandi, recently underwent training stints with top European clubs such as Newcastle United, Chelsea, FC Metz and Atletico Madrid.

His latest move to Metz sees him undergo training and compete for their U-19 team, while furthering his studies there.

The former U-16 captain said he chose the French club as he liked his experience there and the club is renowned for its youth academy.

The Football Association of Singapore was behind the partnership and is looking at sending more youths for such exposure.

- CNA/fa



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PM to visit Hyderabad tomorrow

NEW DELHI: Prime Minister Manmohan Singh will visit Hyderabad tomorrow to take stock of the situation in the aftermath of twin bomb blasts there.

Singh will visit the hospital where the injured are being treated besides taking a briefing from chief minister Kiran Reddy, sources said.

Two bombs exploded within a span of minutes in Hyderabad on Thursday evening, killing 16 people and injuring 117.

The central government yesterday came under sharp attack in Parliament, with the Opposition saying terror was being dealt with in a casual manner.

Strongly condemning the blasts, the Prime Minister had said soon after the incident that those responsible for the "dastardly" act would not go unpunished.

He appealed to the public to remain calm and maintain peace.

Singh has sanctioned Rs 2 lakh each to next of kin of those killed in the blasts and Rs 50,000 each to those seriously injured from the PM's Relief Fund.

Investigators today claimed to have got "vital clues" in the probe, with the needle of suspicion zeroing in on banned militant outfit Indian Mujahideen.

Police announced Rs 10 lakh award for information leading to the perpetrators of the serial blasts.

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FDA approves new targeted breast cancer drug


WASHINGTON (AP) — The Food and Drug Administration has approved a first-of-a-kind breast cancer medication that targets tumor cells while sparing healthy ones.


The drug Kadcyla from Roche combines the established drug Herceptin with a powerful chemotherapy drug and a third chemical linking the medicines together. The chemical keeps the cocktail intact until it binds to a cancer cell, delivering a potent dose of anti-tumor poison.


Cancer researchers say the drug is an important step forward because it delivers more medication while reducing the unpleasant side effects of chemotherapy.


"This antibody goes seeking out the tumor cells, gets internalized and then explodes them from within. So it's very kind and gentle on the patients — there's no hair loss, no nausea, no vomiting," said Dr. Melody Cobleigh of Rush University Medical Center. "It's a revolutionary way of treating cancer."


Cobleigh helped conduct the key studies of the drug at the Chicago facility.


The FDA approved the new treatment for about 20 percent of breast cancer patients with a form of the disease that is typically more aggressive and less responsive to hormone therapy. These patients have tumors that overproduce a protein known as HER-2. Breast cancer is the second most deadly form of cancer in U.S. women, and is expected to kill more than 39,000 Americans this year, according to the National Cancer Institute.


The approval will help Roche's Genentech unit build on the blockbuster success of Herceptin, which has long dominated the breast cancer marketplace. The drug had sales of roughly $6 billion last year.


Genentech said Friday that Kadcyla will cost $9,800 per month, compared to $4,500 per month for regular Herceptin. The company estimates a full course of Kadcyla, about nine months of medicine, will cost $94,000.


FDA scientists said they approved the drug based on company studies showing Kadcyla delayed the progression of breast cancer by several months. Researchers reported last year that patients treated with the drug lived 9.6 months before death or the spread of their disease, compared with a little more than six months for patients treated with two other standard drugs, Tykerb and Xeloda.


Overall, patients taking Kadcyla lived about 2.6 years, compared with 2 years for patients taking the other drugs.


FDA specifically approved the drug for patients with advanced breast cancer who have already been treated with Herceptin and taxane, a widely used chemotherapy drug. Doctors are not required to follow FDA prescribing guidelines, and cancer researchers say the drug could have great potential in patients with earlier forms of breast cancer


Kadcyla will carry a boxed warning, the most severe type, alerting doctors and patients that the drug can cause liver toxicity, heart problems and potentially death. The drug can also cause severe birth defects and should not be used by pregnant women.


Kadcyla was developed by South San Francisco-based Genentech using drug-binding technology licensed from Waltham, Mass.-based ImmunoGen. The company developed the chemical that keeps the drug cocktail together and is scheduled to receive a $10.5 million payment from Genentech on the FDA decision. The company will also receive additional royalties on the drug's sales.


Shares of ImmunoGen Inc. rose 2 cents to $14.32 in afternoon trading. The stock has ttraded in a 52-wek range of $10.85 to $18.10.


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Oscar Pistorius Sobs as Bail Ruling Is Expected












The fourth and likely final day of the bail hearing for Oscar Pistorius, the Olympian accused of murdering his girlfriend Feb. 14, opened with arguments from the prosecution that the runner's version of events is improbable and the defense countering that Pistorius had no intent to kill the woman.


Pistorius, who gained global acclaim for racing at the 2012 London Olympics, shot his model-girlfriend through a closed bathroom. He says he killed Reeva Steenkamp accidentally, but prosecutors allege that he took a moment to put on his prosthetic legs, indicating that he thought out and planned to kill Steenkamp when he shot her three times through the bathroom door.


Pistorius sobbed today in court. Barry Roux, his defense attorney, said the prosecution has misinterpreted the assigning of intent, meaning that the runner's intent to shoot at a supposed intruder in his home cannot be transferred to someone else who was shot -- in this case, Steenkamp.


"He did not want to kill Reeva," Roux told the court.


PHOTOS: Paralympics Champion Charged in Killing


When Magistrate Desmond Nair, who has been overhearing the bail hearing, asked Roux what the charges should be if Pistorius intended to kill an intruder, the defense attorney responded that he should be charged with culpable homicide.


Culpable homicide is defined in South Africa as "the unlawful negligent killing of a human being."








Oscar Pistorius: Detective Facing Attempted Murder Charges Watch Video









Oscar Pistorius: Investigator Faces Attempted Murder Charges Watch Video









Oscar Pistorius's Bail Hearing: Prosecutors Argue Premeditated Murder Watch Video





Roux also made light of the prosecution's argument that Pistorius is a flight risk, saying that every time the double-amputee goes through airport security, it causes a commotion. He said that Pistorius' legs need constant maintenance and he needs medical attention for his stumps.


The prosecution argued today that the onus is on Pistorius to provide his version of events, and his version is improbable.


Prosecutor Gerrie Nel also spoke of Pistorius' fame and his disability, even relating him to Wikipedia founder Julian Assange, who is now confined to Ecuador's London Embassy, where he has been granted political asylum.
"[Assange's] facial features are as well known as Mr. Pistorius' prostheses," Nel said.


Nel argued that Pistorius' prostheses do not set him apart, stating that it's no different to any other feature, and the court cannot be seen to treat people with disabilities accused of a crime, or famous people accused of crime, any differently.


Pistorius has said that in the early hours of Feb. 14 he was closing his balcony doors when he heard a noise from the bathroom. Fearing an intruder, and without his prosthetic legs on, he grabbed a gun from under his bed and fired through the closed bathroom door, he told the court.


But prosecutors say that's implausible, that the gun's holster was found under the side of the bed where Steenkamp slept, and that Pistorius would have seen she wasn't there. Prosecutors also say the angle at which the shots were fired shows Pistorius was already wearing his prosthetics when he fired.


Meanwhile, Lt. General Vinesh Moonoo was named Thursday the new chief investigator to the murder case after the surprise revelation that the former head detective and the prosecution's key witness, Hilton Botha, was charged with seven counts of attempted murder in connection to a 2011 shooting. The charges against Botha amount to an significant oversight by the state, which could sway the court's opinion.


Prosecutors maintain that Pistorius was out to kill on the night of Valentine's Day, prompting him to fire four shots into the locked bathroom door that Steenkamp was behind.


Friends of the couple say they were happy, and there is no reason why Pistorius would intentionally hurt Steenkamp.


"If Oscar was to ask her to get married, she would have said yes," friend Kevin Lerena said. "That's how happy and joyful their relationship was."


Ampie Louw, Pistorius' trainer, spoke with reporters outside the courthouse today, saying that he hopes Pistorius gets bail and can start training again, but that he won't push it.


"I'm not the legal side of it. But I'm ready," he said. "We can start training Monday if he's out."



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Iran appears to advance in construction of Arak nuclear plant


VIENNA (Reuters) - Iran appears to be advancing in its construction of a research reactor Western experts say could offer the Islamic state a second way of producing material for a nuclear bomb, if it decided to embark on such a course, a U.N. report showed.


Iran has almost completed installation of cooling and moderator circuit piping in the heavy water plant near the town of Arak, the International Atomic Energy Agency (IAEA) said in a confidential report issued to member states late on Thursday.


Nuclear analysts say this type of reactor could yield plutonium for nuclear arms if the spent fuel is reprocessed, something Iran has said it has no intention of doing. Iran has said it "does not have reprocessing activities", the IAEA said.


In its previous report on Iran, in November, the Vienna-based U.N. agency said installation work at Arak was continuing, without giving any indication of how far advanced it was.


Iran rejects Western allegations it seeks to develop a capability to assemble nuclear weapons, saying its atomic program is entirely peaceful and that the Arak reactor will produce isotopes for medical and agricultural use.


Iran says it plans to begin operating the facility in the first quarter of 2014, the IAEA said. Tehran last year postponed the planned start-up from the third quarter of 2013, a target that Western experts said always had seemed unrealistic.


The Arms Control Association, a Washington-based research and advocacy group, said late last year that it was questionable whether Iran would be able to meet the new target date as well, in view of "significant delays and impeded access to necessary materials" because of international sanctions imposed on Iran.


Western worries about Iran are focused largely on uranium enrichment plants at Natanz and Fordow, as such material refined to a high level can provide the fissile core of an atomic bomb. But experts say Arak may also be a proliferation issue.


The Arak facility is a "growing source of concern", said Mark Fitzpatrick, director of the non-proliferation and disarmament program of the International Institute for Strategic Studies (IISS), a London-based think-tank.


Israel, believed to be the Middle East's only nuclear-armed state, sees Iran's nuclear program as a serious danger and has threatened to attack its atomic sites if diplomacy and sanctions fail to resolve the decade-old dispute.


If it does, the nuclear sites at Natanz, Fordow and Arak in central Iran are likely to be targets. Fitzpatrick said it could be Arak that triggers a conflict because attacking it after it is launched could cause an environmental disaster.


TESTING FUEL FOR ARAK REACTOR


Thursday's quarterly IAEA report showed Iran expanding its uranium enrichment program in defiance of tightening Western sanctions, installing advanced centrifuge machines at its main enrichment plant near the town of Natanz.


The report, issued just a few days before six world powers and Iran are due to resume negotiations after an eight-month hiatus, underlined the tough task facing the West in seeking to pressure Tehran to curb its nuclear activities.


Cliff Kupchan, Middle East director at the Eurasia consultancy, said Iran had adopted a defiant policy of pressing ahead with its nuclear program, despite harsh sanctions.


"As a result, Israel and the U.S. Congress will press a receptive U.S. administration to move forward with new and even harsher sanctions," he said in a research note.


Enriched uranium can fuel nuclear power plants, Iran's stated aim, but also provide the explosive core of a nuclear weapon if refined much further. Making plutonium from spent fuel is a second way of obtaining potential bomb material.


The Institute for Science and International Security (ISIS), a U.S. think-tank, noted that Iran planned to use a medical research reactor in Tehran, known as TRR, to test fuel for Arak.


"The TRR is now more than a medical isotope production reactor, Iran's stated use for the reactor, and is necessary for the operation" of Arak, it said in a report.


If operated optimally, the heavy-water plant could produce about nine kilograms (20 pounds) of plutonium a year, or enough for about two nuclear bombs annually, ISIS has said previously.


"Before it could use any of the plutonium in a nuclear weapon, however, it would first have to separate the plutonium from the irradiated fuel," it added on its website.


Iran has repeatedly declared it has no plans to reprocess the spent fuel. But, "similarly sized reactors ostensibly built for research" have been used by India, Israel, North Korea and Pakistan to make plutonium for weapons, Fitzpatrick said.


(Editing by Mark Heinrich)



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Gossip scandal erupts in Vatican ahead of Pope's exit






VATICAN CITY: With just days to go before Pope Benedict XVI's resignation, the Vatican is battling persistent rumours that his decision was triggered by an explosive report on intrigue in its corridors of power.

The secret report compiled by a committee of three cardinals for the Pope's eyes only was the result of a wide-ranging investigation into leaks of confidential papers from the Vatican that caused huge embarrassment last year.

The cardinals questioned dozens of Vatican officials and presented the Pope with their final report in December 2012, just before Benedict pardoned his former butler Paolo Gabriele who had been convicted of leaking the papal memos.

The Panorama news weekly and the Repubblica daily said on Thursday that the report contained allegations of corruption and of blackmail attempts against gay Vatican clergymen, as well as favouritism based on gay relationships.

Both publications quoted a source with knowledge of the investigation saying that the cardinals' conclusions "revolve around the sixth and seventh commandments" -- "Thou shall not commit adultery" and "Thou shall not steal".

The Vatican has declined to comment on these two reports, with spokesman Federico Lombardi saying they were "conjectures, fictions and opinions."

The run-up to papal conclaves to elect a new Pope is often accompanied by rumours and gossip in Italian media, as rival factions battle for influence.

But there was a twist on Friday when Pope Benedict XVI replaced Monsignor Ettore Balestrero, a powerful behind-the-scenes figure in the Secretariat of State with a major role in handling the Vatican bank's foreign relations.

He is being sent as Vatican envoy to Colombia -- a serious demotion.

Balestrero has been a key figure in Vatican efforts to overhaul its scandal-tainted bank to comply with international anti-money laundering laws.

La Repubblica said Balestrero's name was mentioned in the cardinals' report.

A Vatican expert at Italian daily La Stampa said the Pope would likely meet with the three retired cardinals who authored the report before resigning.

The report could also be discussed during a series of meetings for cardinals beginning next Friday, a day after the Pope steps down, where priorities for the Catholic Church will be debated and potential papal candidates sussed out.

The "Vatileaks" scandal first exploded in January last year when Italian media published a series of letters to the Pope in which Carlo Maria Vigano, the head of the Vatican City's government denounced corruption and waste.

The following leaks pointed to divisions in the Vatican hierarchy including efforts to unseat Secretary of State Tarcisio Bertone, a divisive figure.

On May 23, Gabriele was arrested and his house inside the Vatican walls was raided by special gendarmes who found hundreds of sensitive documents.

A day later, the head of the Vatican bank, Ettore Gotti Tedeschi, was sacked, accused of mismanagement and indiscretions linked to the leaks.

Gabriele was convicted after a week-long trial in the Vatican in October.

The Pope asked cardinals to investigate last year, giving them free rein to interview anyone of the 2,843 people working in the Roman Curia and 2,001 people working for the governorate, the administration of the Vatican City.

The committee was also allowed to collect testimony from cardinals.

-AFP/fl



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Afzal's family hasn't approached us: Tihar DG

NEW DELHI: The family of Afzal Guru, who was hanged two weeks ago at Tihar jail, has not yet approached the prison authorities to pray at his grave though the government has made the offer for his close relatives.

"We have not received any letter from Guru's family in this regard," Director General of Tihar Prisons Vimla Mehra told reporters.

The government has already said it will allow Guru's close relatives to visit his grave, an offer rejected by the family which has been insisting on return of his body to them.

Asked whether jail authorities will allow family members to visit Guru's grave if they make a request, Mehra refrained from giving a direct reply, saying "the government is considering it."

On the criticism that the letter sent to Guru's family informing about his hanging reached two days after his execution, Mehra said, "It was a job (Afzal's hanging) assigned to us and we followed the official procedure to execute it."

Guru was hanged at Tihar jail on February 9 in a top secret operation after his final appeal for mercy was rejected by President Pranab Mukherjee. His body was buried inside the jail premises.

Addressing an annual press conference, the DG also listed various activities undertaken at the jail in the past one year.

She said a blanket making unit was established at jail number nine this year where 80 convicts are working currently. The unit supplies blankets to Delhi Police and Delhi Health Department.

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